Celta de Vigo
Hugo González is doubtful after his recent discomfort was diagnosed as an adductor overload, and his availability against Union Sint-Gillis remains uncertain. The winger has started twice in his last five matches and is not expected to start here.
Marcos Alonso should return on the left after not playing against Rayo Vallecano, with Sebastián Cáceres expected to continue in the back line. Ionuț Radu is set to remain in goal after five consecutive starts, while Javi Rodríguez should retain his place after scoring three goals and providing an assist during the same run. Iago Aspas is expected to return to the starting side.
Union Sint-Gillis
Guilherme Smith is expected to continue in the side after starting each of the last five matches and scoring three goals. Dylan Aquino, who appeared for eight minutes in the last outing, could be suspended after the Belgian FA prosecutor proposed a two-match ban for his red card against Beveren; Union had not yet accepted the proposal. Kevin Rodríguez, handed his first start in that same match, was withdrawn at half-time as a planned step in his return to fitness and is not expected to start against Celta de Vigo.
Nikki Havenaar is expected in the back three alongside Nohim Chibani and Massiré Sylla. Ahead of them, Louis Patris and Besfort Zeneli have started every match in this stretch, with Patris contributing a goal and two assists, while Relebohile Mofokeng has added a goal and two assists. Union sit sixth with seven points after a 4-0 win over Hapoel Beer Sheva in their last match in this competition.