Porto
Porto's emphatic win over Estoril offered a welcome contrast to their Champions League campaign, where three matches have yet to produce a point. Francesco Farioli has made it clear that his team will not abandon its aggressive approach following the home defeat to PSV, although he expects a very different tactical challenge from Napoli.
The bigger decisions concern the attacking positions. Farioli has ruled William Gomes out, while Oskar Pietuszewski has returned to training but still requires an assessment. Borja Sainz therefore looks a plausible starter on the left, with Pepê on the opposite flank. Samu Aghehowa started the weekend league game, but André Silva remains a genuine alternative through the middle. Gabri Veiga, Pablo Rosario and Victor Froholdt have formed a familiar midfield combination. Porto will need their pressing to create opportunities without leaving space for Napoli to exploit on the break.
Napoli
Napoli's preparations have been dominated by the loss of their full-backs. Giovanni Di Lorenzo and Mathías Olivera returned to Italy for medical assessments after the Juventus match, while Leonardo Spinazzola is also unavailable. With Luca Marianucci omitted from the Champions League squad, Massimiliano Allegri has very little flexibility in defence.
A back three of Sam Beukema, Amir Rrahmani and Rafa Marín would allow Matteo Politano and Noa Lang to cover the wide positions. That arrangement asks Lang to operate deeper than his usual attacking role, a significant adjustment against a Porto side intent on pressing high. Billy Gilmour is a potential replacement for the injured Stanislav Lobotka. Kevin De Bruyne travelled with the squad but remains doubtful with an ankle problem, while Rasmus Højlund was training individually after illness. Lorenzo Lucca and Giovane offer alternatives in attack. Napoli's priority will be finding a stable structure despite the extensive absences.
