RB Leipzig
Antonio Nusa helped Leipzig beat Schalke 2-0 on Saturday, scoring from the penalty spot and then setting up Rômulo. It was their first away league win of the campaign and a timely boost before facing a Manchester City side capable of dominating possession. Leipzig have won only once in their first three Champions League games. Assan Ouédraogo and Marc Guiu are ruled out, while Maxime Estève remains a doubt.
Martín Demichelis has an interesting midfield decision. Ezechiel Banzuzi has started the last two domestic fixtures, while Nicolas Seiwald, Neil El Aynaoui and Rocco Reitz offer different combinations. Leipzig could return to a 4-2-3-1, with Christopher Nkunku behind Rômulo, although Christoph Baumgartner is pushing for minutes after scoring twice in the German Cup. Nusa's direct running and Brajan Gruda's movement from the opposite flank could be particularly useful if Leipzig are forced to defend for long periods.